This course will first examine the effects of acute and chronic stressors on the body’s systems, including the immune system, cardiovascular system, endocrine system, and markers of cellular aging, and how stressors can influence well-being habits such as sleep. We will then connect these physical and mental changes to health outcomes, including increased risk of depression, cardiovascular disease, infectious illness, and mortality. The above will provide a better understanding of the pathways through which stressors can influence health and mindset. Then, we will examine how different factors may help us better regulate our physiological and behavioral responses to stressors. Finally, we will review research elucidating how mind-body practices like meditation and yoga can lead to positive shifts in physiological parameters and help us better respond to stressful conditions. With guided breath, meditation, and yoga practices interspersed throughout, you can learn to apply these techniques in your own lives. Additionally, we will discuss the critical role of social relationships in helping us improve health and manage the different stressors we encounter.